Automate Biomaterials R&D

Robotics and AI-driven R&D, getting formulations into animal and clinical studies faster and cheaper, with stronger in vivo/in vitro correlations.

Faster to market with larger, more reliable in vitro datasets

Reach a final formulation faster, with data closer to in vivo conditions.

Track all of these in a single Carousel run

6 samples at a time, measured continuously, around the clock.

  1. 01
    Swelling and hydration
    • Gravimetric
    • Volumetric
    • Absorbency under load
    • Vapor transmission
  2. 02
    Degradation
    • Enzymatic
    • Accelerated
    • Hydrolytic
  3. 03
    Release
    • Drug
    • Extractables and leachables
    • UV-Vis, LC-MS, HPLC, ELISA
  4. 04
    Computer vision
    • Optical properties
    • Color
    • Transparency
    • Morphology
  5. 05
    pH
    • Monitored in line
    • pH 1.5 to 12
  6. 06
    Mechanical properties
    • Stiffness
    • Mesh size
    • Crosslink density

    Method suitable for synthetic polymers only.

21 CFR Part 11 compliant

One Carousel run captures the complete product lifecycle

See your gel take up fluid, release its drug and break down in one automated run, so weeks to months of testing take 10 to 20 minutes of your team's time.

Swelling/degradation and drug released

Illustrative · one point per automated 24/7 measurement

Illustrative chart of one gel sample's swelling and degradation, as its mass ratio to the initial dry mass, and the cumulative % of its drug released through one test.

Swelling, antimicrobial released and wound pH

Illustrative · one point per automated 24/7 measurement

Illustrative chart of a wound dressing's swelling, as its mass ratio to the initial dry mass, the cumulative % of its antimicrobial released, and the wound bed's pH, neutral to slightly alkaline when fresh (about 7.8) and acidifying toward intact skin's pH (about 5.5) as it heals.

Scaffold swelling/resorption and new tissue

Illustrative · one point per automated 24/7 measurement

Illustrative chart of a hydrogel scaffold in a knee cartilage defect: its mass ratio to the initial dry mass as it swells to press-fit the defect and is then resorbed, and the % of the defect new cartilage has filled.

Swelling, deswelling and biodegradation

Illustrative · one point per automated 24/7 measurement

Illustrative chart of a soil hydrogel's water held per gram through two rains (shaded) and dry spells, then its biodegradation.

Swelling

Illustrative · one point per automated 24/7 measurement

Illustrative chart of a superabsorbent's swelling in a diaper, as its mass ratio to the initial dry mass, through one test.

  • 10xLower costsLabor and consumables per datapoint.
  • 7xMore data generationTesting runs 168 hours a week, not 40.
  • 3xHigher precisionLower sample-to-sample variability than manual gravimetric methods.

Compared with manual methods.

Plan your study on a virtual Carousel

Set up a run, then see what it records.

Try the virtual demo

Free, in your browser, no sign-up.

Backed byLeading research institutions and venture capital

  • National Science Foundation
  • SLAS
  • UC San Diego Jacobs School of Engineering
  • Treeo VC
  • Phase Two Ventures
  • NextFab Ventures
  • Institute for the Global Entrepreneur
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